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Image Search Results
Journal: Digestive diseases and sciences
Article Title: Disruption of GPR35 Exacerbates Dextran Sulfate Sodium-Induced Colitis in Mice
doi: 10.1007/s10620-018-5216-z
Figure Lengend Snippet: Neutrophil and eosinophil numbers in the colonic submucosa and mucosa in the colons of GPR35+/+ and GPR35−/− mice administered DSS. Multiple high-power fields (HPF, 400 ×) of regions representing the different scores of crypt damage in the mucosa and submucosa were pooled from each mouse into a single score, and the scores of different mice were pooled to derive a mean ± SEM. The numbers of neutrophils or eosinophils were counted in each area of the different scores of crypt damage. a The numbers of neutrophils in the submucosa and mucosa in each score category of crypt damage. b The numbers of eosinophils in the submucosa and mucosa in each score category of crypt damage. In both graphs, no statistical significance has been found between GPR35+/+ and GPR35−/− mice administered with DSS in each score category of crypt damage. c Representative high-power photomicrograph of Congo redstained section in DSS-inflamed GPR35+/+ mouse colon mucosa. Red staining distinguishes eosinophils (red arrows) from unstained neutrophils (blue arrows)
Article Snippet: Differentiation between neutrophils and eosinophil granulocytes was performed on paraffin-embedded colon slides (5-μm-thick sections) using
Techniques: Staining